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Xilong Scientific Co Ltd Isopropyl Alcohol

    • Product Name: Xilong Scientific Co Ltd Isopropyl Alcohol
    • Factroy Site: Binhai New Area, Tianjin, China
    • Price Inquiry: sales4@ascent-chem.com
    • Manufacturer: Ascent Petrochem Holdings Co., Limited
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    Specifications
    HS Code 465835
    Product Name Xilong Scientific Co Ltd Isopropyl Alcohol
    Cas Number 67-63-0
    Molecular Formula C3H8O
    Molecular Weight 60.10 g/mol
    Purity ≥99.7% (AR grade)
    Appearance Clear colorless liquid
    Boiling Point 82.5°C
    Flash Point 11.7°C (closed cup)
    Density 0.785 g/cm³ at 25°C
    Solubility Miscible in water, ethanol, and ethyl ether

    As an accredited Xilong Scientific Co Ltd Isopropyl Alcohol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing The packaging is a 500 mL amber glass bottle with a white screw cap, labeled with product details and safety warnings.
    Container Loading (20′ FCL) 20′ FCL container loading of Xilong Scientific isopropyl alcohol: secure drum palletization, proper segregation, ventilation, and compliant hazardous goods handling.
    Shipping Ship as UN1219, Isopropanol, Class 3 flammable liquid, Packing Group II. Use approved containers, secure upright, and apply hazard labels. Provide SDS, dangerous goods declaration, and comply with carrier restrictions. Ground transport preferred; air shipment requires IATA-compliant packaging. Avoid extreme heat and ignition sources during transit.
    Storage Store isopropyl alcohol in a cool, dry, well-ventilated area away from heat, sparks, and open flames. Keep the container tightly closed and upright, preferably in an approved flammable-liquid cabinet. Avoid contact with strong oxidizers. Use grounded containers and bonding to prevent static discharge, and ensure that storage areas are clearly labeled and accessible for emergency response.
    Shelf Life Shelf life is typically 2-3 years when stored in tightly sealed containers away from heat and light.
    Application of Xilong Scientific Co Ltd Isopropyl Alcohol

    In surface-mount assembly lines, isopropyl alcohol supplied at 99.9 wt% anhydrous specification is charged into automated stencil-cleaning systems. The solvent dissolves rosin-based flux residues and no-clean flux activators from solder paste deposits. Equipment operating in this segment includes pneumatic stencil cleaners with 40–60 kHz ultrasonic transducers and inline wash systems with air-knife drying stages. Published data for this specific configuration is limited. However, IPC J-STD-001H Clause 8.3.5 requires that bare board and assembly residues be removed to a level that does not compromise electrical performance. Ionic contamination verification follows IPC TM-650 Method 2.3.25. The pass/fail threshold is 1.56 µg/cm² NaCl equivalent for most Class 2 and Class 3 assemblies. The solvent's evaporation rate of 2.3 relative to n-butyl acetate permits post-clean drying at ambient conditions within 90–180 seconds on stencil surfaces at 22°C. Process control hinges on maintaining anhydrous conditions. Water content above 0.2 wt% slows evaporation and promotes white residue deposition on board surfaces. Flash point of 12°C mandates exhaust ventilation at 30 m/min face velocity at open cleaning stations. Material incompatibility is documented for acrylic adhesives used in some stencil tensioning frames. Swelling occurs after prolonged immersion beyond 30 minutes. Acetone and MEK blends are avoided in this segment because their aggressive solvency attacks solder mask coatings. Isopropanol at 99.9% leaves epoxy-based solder masks intact after 300 immersion cycles. The terminal product is a fully assembled surface-mount PCB ready for ICT and functional testing.

    What Compounding Ratio Triggers WHO Acceptance in Isopropanol-Based Hand Rub Formulations?

    The WHO-validated formulation for isopropanol-based hand rub specifies three active components. Isopropanol is present at 75.0% v/v. Glycerol is added at 1.45% v/v. Hydrogen peroxide is added at 0.125% v/v. The remaining volume is sterile distilled water. The formulation is defined in the WHO Guidelines on Hand Hygiene in Health Care. It has been adopted by national pharmacopoeias for local production. Isopropanol for this application must meet USP monograph or equivalent pharmacopoeial specifications. Impurity profiles are verified by gas chromatography. The glycerol acts as a humectant to reduce skin dryness. Hydrogen peroxide provides sporicidal activity during the 72-hour post-compounding hold period. The compounding sequence is strictly ordered. Isopropanol is added to the mixing vessel first. Glycerol is added second. Hydrogen peroxide is added third. Water is added last. Stirring is maintained at low shear for 10–15 minutes to avoid aeration. The finished solution is filled into high-density polyethylene bottles of 100 mL, 500 mL, or 1 L capacity. Batch release testing includes density measurement at 20°C and refractive index determination. Chromatographic purity assay confirms isopropanol content within ±2.0% of label claim. Ethanol is not substituted in this formulation. The WHO distinguishes between ethanol-based and isopropanol-based ABHR recipes. Mixing the two systems is not recommended because of differing flammability profiles and skin tolerance data. Storage at temperatures above 35°C accelerates peroxide degradation. The formulation carries a category 3 flammable liquid classification under GHS. Storage in ventilated chemical cabinets away from oxidizers is mandated. Production-scale observations document that hydrogen peroxide addition to unmixed isopropanol can cause thermal stratification in the vessel. Inline static mixers of 12–18 elements are recommended for homogenization in lots exceeding 200 L. The terminal product is a shelf-stable alcohol-based hand rub packaged for institutional healthcare use.

    Table 1 — WHO IPA-Based ABHR Compounding Matrix
    ComponentConcentration (% v/v)FunctionReference Specification
    Isopropanol75.0%Antimicrobial activeUSP/Ph.Eur monograph
    Glycerol1.45%HumectantUSP/Ph.Eur monograph
    Hydrogen peroxide0.125%Sporicidal during 72-hour holdPh.Eur 3% solution monograph
    Purified waterq.s. to 100%DiluentUSP Purified Water

    Anilox Roll Starvation and Ink Viscosity Management on Central-Impression Flexographic Presses

    Isopropanol functions as the primary viscosity-reducing solvent in solvent-based flexographic inks. The ink concentrate is supplied at 50–60 seconds Zahn cup #2 viscosity. Press-ready viscosity is achieved by adding isopropanol at 5.0–15.0 wt% of ink concentrate mass. The target viscosity range is 18–28 seconds Zahn cup #2 for linework and solids at 40–55 LPI anilox line counts. For process-color printing at 60–85 LPI anilox, viscosity is adjusted to 14–18 seconds. The solvent is metered through closed-loop viscosity controllers connected to the ink sump. These controllers maintain ±1 second variance. Excess isopropanol addition below 10 seconds causes anilox starvation. Ink fails to transfer adequately from the anilox cells to the plate. Ghosting appears in the printed image. Addition above 25 wt% degrades adhesive bonds in pressure-sensitive label laminates after drying. Residual solvent is trapped in the ink film. Drying is performed in interstation hot-air dryers at 60–80°C air temperature. Single-pass drying at 120 m/min web speed on 25 µm BOPP film is achievable. Compliance testing of printed matter for solvent residues follows EN 13628-1 for flexible packaging. Printability verification is conducted per ISO 12647-6 for flexographic printing. The solvent must be anhydrous. Water content above 0.5 wt% precipitates nitrocellulose resins in some ink systems. The terminal product is printed flexible packaging: labels, shrink sleeves, and sachet laminates.

    Table 2 — Flexographic Ink Viscosity Adjustment Data
    Press configurationAnilox LPIViscosity (Zahn #2, sec)IPA addition (wt%)Drying air temp (°C)
    Linework / solids40–5518–285.0–8.060–70
    Process color60–8514–188.0–15.070–80
    Fine process work90–12012–1410.0–15.075–85

    Chromatographic-grade isopropanol serves as a mobile-phase modifier for reversed-phase HPLC method development. Its measured dynamic viscosity of 2.04 mPa·s at 25°C limits its use in binary aqueous eluents to 20.0% v/v maximum. Above this threshold, column backpressure exceeds system limits on standard 5 µm particle columns at 1.0 mL/min flow. The solvent passes through 0.22 µm membrane filtration before mixing with heptane or hexane mobile phases. Isopropanol content in normal-phase mobile phases ranges from 1.0% to 20.0% v/v. UV absorbance at 215 nm must remain below 0.05 AU for gradient suitability. Analytical reagent specifications per ISO 6353-2 govern chromatographic-grade isopropanol. Published data for specific column configurations is limited. The terminal output is a validated separation report supporting pharmaceutical release testing.

    Freeze-Point Depression at −20°C Dictates Concentrated Screen Wash Blending

    Where cold-weather ambient conditions reach −25°C, isopropanol is blended into automotive screen wash concentrates. The concentrate is formulated at 70.0% v/v isopropanol in deionized water. This provides freeze protection to approximately −30°C. The freeze point is verified by ASTM D1177 for coolant-type aqueous solutions. Dilution at 1:1 with tap water shifts the freeze point to approximately −14°C. This is inadequate for Scandinavian winter conditions where ambient temperatures reach −25°C. The concentrate also incorporates 0.5–2.0 wt% of anionic surfactants for road film removal. A bittering agent is added at 0.1 wt% to prevent accidental ingestion. Surfactant selection is restricted to short-chain sulfonates that remain soluble at 70% isopropanol. Nonionic ethoxylated surfactants above 0.5 wt% cause phase separation at −5°C storage. The concentrate is filled into 5 L HDPE jerry cans. GHS labeling requires the flammable liquid pictogram and the serious eye irritation pictogram. The product is classified as UN 1219 for transport. The terminal product is a ready-to-use windshield washer fluid sold in retail packaging for winter driving.

    The nitrocellulose lacquer segment consumes isopropanol as a diluent that extends the active solvent blend without dissolving the resin. The lacquer base is compounded from 8.0–15.0 wt% nitrocellulose. Plasticizer content is 10.0–20.0 wt%, typically dibutyl phthalate or acetyl tributyl citrate. Primary solvents, comprising esters and ketones, account for 50.0–65.0 wt%. Isopropanol is added at 3.0–8.0 wt%. The diluent extends the evaporation window of the solvent blend, preventing blushing at relative humidity above 65%. Blushing is a haze defect caused by moisture condensation during rapid cooling of the film. Standard practice per ASTM D333 specifies viscosity measurement with a Ford #4 viscometer at 25°C. Target application viscosity is 20–25 seconds. The lacquer is applied by spray gun at 0.28–0.35 MPa atomizing air pressure. Film thickness is controlled at 25–35 µm dry. Isopropanol content above 8.0 wt% slows film cure. Residual odor persists in the finished coating. The lacquer system is subject to VOC restrictions under local regulations. Equipment cleaning for spray booths uses 99.9% isopropanol as the primary wash solvent for gravity-feed spray guns. Flushing volumes are 100–200 mL per gun per color change. The terminal product is a coated wooden furniture surface or a coated metal component with a nitrocellulose finish.

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    Certification & Compliance
    More Introduction

    Xilong Scientific Co Ltd supplies isopropyl alcohol (2-propanol; CAS 67-63-0; EC 200-661-7; molecular mass 60.10 g mol-1) as a low-boiling, fully water-miscible polar solvent for laboratory, chromatographic, electronics-cleaning, and extraction workflows. The product is identified by purity tier rather than by a single proprietary model code; standard catalogue descriptors include analytical reagent, chemically pure, high-performance liquid chromatographic, and electronic solvent configurations in nominal volumes of 500 mL, 2.5 L, 4 L, 25 L, and 200 L. Representative release values include an assay of ≥99.7% by GC-FID, a density at 20 °C between 0.785 g/cm³ and 0.789 g/cm³, and a water content not exceeding 0.20% w/w for analytical reagent and chemically pure material when tested by ASTM E203 Karl Fischer titration. Batch-specific certificates of analysis remain the controlling documents because filling-line humidity, container headspace oxygen, and storage temperature can shift water and carbonyl-related impurities during shelf life.

    Product Identity and Release Architecture

    The release profile, package closure, and purity tier define the operating province of the solvent. Analytical reagent material is supplied in borosilicate glass or high-density polyethylene with vapour-tight closures; high-performance liquid chromatography grade is typically filled into amber glass or nitrogen-purged high-density polyethylene to limit UV-absorbing degradation products and water ingress. High-performance liquid chromatography grade is controlled to an assay of ≥99.8%, water content ≤0.05% w/w, evaporation residue ≤5 ppm, and titratable acid as acetic acid ≤0.001% w/w. Chemically pure material carries a broader residue and water envelope and is directed toward routine wet-chemistry operations rather than trace organic analysis. Electronic solvent configurations add metal, particle, and absorbance specifications absent from chemically pure and analytical reagent tiers. The amber-glass and low-headspace configurations of the high-performance liquid chromatography package are functional measures against light-initiated oxidative degradation, which converts isopropanol to acetone and water and can alter detector baselines at wavelengths approaching the solvent cutoff near 205 nm.

    Nominal release specifications for Xilong isopropanol purity tiers
    ParameterAnalytical reagent / chemically pure criterionHigh-performance liquid chromatography criterionTest reference
    Assay by GC-FID≥99.7%≥99.8%ASTM D770
    Density at 20 °C0.785–0.789 g/cm³0.785–0.789 g/cm³ASTM D4052
    Refractive index n20D1.376–1.3781.376–1.378ASTM D1218
    Distillation range at 101.3 kPa81.5–83.0 °C81.5–83.0 °CASTM D86
    Water content by Karl Fischer titration≤0.20% w/w≤0.05% w/wASTM E203
    Evaporation residue≤50 ppm≤5 ppmASTM D1353
    Acidity as acetic acid≤0.002%≤0.001%ASTM D1613
    Ultraviolet transmittance at 260 nmnot routinely specified≥90%internally controlled spectrophotometric method

    What Differentiates Analytical-Reagent IPA from Technical or Denatured Solvent Streams?

    Technical-grade isopropanol is frequently sold at ≥99.0% but permits water, acidity, non-volatile residue, and carbonyl impurities at levels one to two orders of magnitude greater than the analytical reagent tier. Some industrial solvent streams additionally contain denaturants such as denatonium benzoate or added methanol that are not disclosed on generic labels; these additives produce chromatographic solvent fronts, UV-absorbing artefacts, and metal residues when carried into analytical systems. Xilong analytical reagent, chemically pure, and high-performance liquid chromatography grades are supplied without denaturant addition, and the certificate of analysis reports methanol and acetone levels when GC-FID data are generated. For high-performance liquid chromatography use, the decisive difference is not bulk assay but the concentration of non-volatile residue and low-wavelength UV-active species that accumulate on reversed-phase columns and degrade detector signal-to-noise. An industrial isopropanol at 99.5% may be acceptable for rough degreasing yet can produce baseline saturation at 260 nm when used as a 0.5% v/v mobile-phase modifier. Electronic-grade isopropanol differs further because cationic and anionic metal burdens are reduced to sub-ppm levels for wafer contact, while standard analytical reagent material is not specified for particles or trace metal concentration.

    Representative impurity-loading contrast across isopropanol configurations; exact Xilong release values may be stricter and are controlled by the lot certificate
    AttributeTechnical solventAnalytical reagent / chemically pureHigh-performance liquid chromatographyElectronic solvent
    Water content1.0% w/w typical0.20% w/w0.05% w/w0.03% w/w typical
    Evaporation residue100 ppm typical50 ppm5 ppm1 ppm typical
    Ultraviolet transmittance at 260 nmnot specifiednot routinely specified≥90%≥95% tier-dependent
    Denaturantsmay be presentabsentabsentabsent
    Particle and metal profilenot specifiednot specifiedlimitedspecified under SEMI C7 or equivalent

    As a reversed-phase high-performance liquid chromatography mobile-phase modifier, isopropanol increases eluotropic strength above methanol but below acetonitrile on conventional C18 packings; its dynamic viscosity of approximately 2.04 mPa·s at 25 °C raises column backpressure more than methanol, and column thermostating at 35–40 °C is usually required when the organic fraction exceeds 10% v/v. High-performance liquid chromatography grade Xilong isopropanol is used in size-exclusion and reversed-phase separations of hydrophobic polymers, lipids, and derivatised analytes requiring stronger hydrogen-bonding solvation than methanol provides. In extraction and precision cleaning, analytical reagent or high-performance liquid chromatography isopropanol dissolves rosin-based soldering fluxes and polar organic residues from stencil apertures, pump components, optical surfaces, and ultrasonic baths; water-free material is preferred for electronics because it avoids ion-migration residues after drying. For biological disinfection, 70% v/v aqueous isopropanol is typically prepared by the user from concentrated analytical reagent and purified water; the original solvent certificate does not apply to the diluted formulation. In nucleic acid precipitation workflows, isopropanol is added at approximately 0.6–0.7 volume per aqueous sample volume to precipitate DNA or RNA, but the standard analytical reagent certificate does not include nuclease or endotoxin testing, so protocol-specific qualification is required before use. Published data for Xilong isopropanol in any single extraction matrix are limited; matrix-blank recovery and residue testing under end-user conditions should override general solvent specifications.

    When Isopropyl Alcohol Is Used in Semiconductor Cleaning and Latent Extractables Profiling

    In semiconductor front-end process equipment, isopropanol is deployed as a drying agent in Marangoni drying because its surface tension of 21.7 mN/m at 20 °C is lower than water’s 72.8 mN/m, generating a surface-tension gradient that thins the residual water film on wafer surfaces. Standard analytical reagent and high-performance liquid chromatography grades are not qualified for this function; electronic-tier Xilong isopropanol should be selected with certificates reporting trace cation and anion concentrations, sub-ppm non-volatile residue, and particle counts per millilitre. Under semiconductor solvent specifications such as SEMI C7, the acceptable impurity envelope is tighter than high-performance liquid chromatography criteria for sodium, potassium, calcium, iron, copper, zinc, chloride, and sulfate because ionic residues can contribute to gate oxide and interconnect defects. The package top is also a process variable: 200 L drums used in semiconductor supply often require fluoropolymer-lined closures, dedicated solvent distribution lines, and nitrogen blanketing to prevent water absorption during use. Published data for Xilong material in a 300 mm wafer-processing tool are limited; point-of-use qualification with total organic carbon, on-line particle counting, and inductively coupled plasma mass spectrometry extractables data is required before release to production.

    Isopropanol conforms to classification criteria under CLP (EC) No 1272/2008 as Flam. Liq. 2, H225; Eye Irrit. 2, H319; and STOT SE 3, H336. The liquid has a closed-cup flash point of 11.7 °C, a boiling point of 82.5 °C, an autoignition temperature of 399 °C, and lower and upper explosion limits of 2.0% v/v and 12.7% v/v. Storage areas require flameproof electrical classification, continuous ventilation of heavier-than-air vapours, and bonding and grounding during transfer. The solvent should be kept away from strong oxidisers, including chromic acid, nitric acid, and hydrogen peroxide, because exothermic oxidation can produce acetone and oxygenated radical species. Although isopropanol does not readily form peroxides at the rate of diethyl ether, prolonged exposure of partially filled containers to ultraviolet light promotes carbonyl and water formation; high-performance liquid chromatography users should record opened-container hold times and monitor water content and 260 nm absorbance before use in critical mobile phases. Hygroscopic uptake is measurable above 60% relative humidity, so open containers should be resealed immediately. The product is not automatically a pharmaceutical-grade excipient; if the solvent is intended for drug-contact or injection use, the applicable grade must be specified, and residual solvent control should reference ICH Q3C, where isopropanol is a Class 3 solvent with a permitted daily exposure of 50 mg/day.

    Grade Substitution Is Not Governed by Bulk Purity Alone

    The main operational error in solvent selection is replacing high-performance liquid chromatography or electronic-grade isopropanol with technical-grade material because the labelled purity appears close. The relevant control variables are not only GC assay but also the trace impurity profile, container closure, and the analytical release method. For methods using evaporative light scattering or charged aerosol detection, non-volatile residue becomes a direct detection artefact; for ultraviolet and visible detection below 230 nm, carbonyl and unsaturated trace species become the limiting variables. For semiconductor and liquid chromatography–mass spectrometry workflows, metal adducts and electrospray ion suppression caused by non-volatile organics can invalidate a method without any shift in isopropanol assay. Xilong differentiates the product by publishing grade-specific specifications rather than applying a single specification sheet to all applications, and by supplying the high-performance liquid chromatography configuration in amber glass or nitrogen-purged packaging that addresses the degradation pathways relevant to low-wavelength detection. The user should still perform lot screening for water, peroxide-reducing substances, ultraviolet transmittance, and evaporation residue under the specific storage conditions and use interval of the facility.